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MRI cortical thickness in these regions of interest (Fig. 1D) was subsequently determined using in-house scripts using the FSL distancemap function (Smith et al., 2006) to compute an average thickness value, taking as input the manual delineation of the grey matter/white matter boundary and cortical surface.
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We determined the statistical significance of the differences in average thickness values of each layer between each stage.
For a correlation analysis between RNFL thickness and visual field sensitivity, the average thickness values in the superior or inferior 180° were calculated from the raw RNFL data.
In CRVO patients, each of these concentric bands was further divided into four quadrants: superior, inferior, nasal, and temporal where average thickness values were generated.
Mean central macular thickness for all patients measured 249.1+/−20.2 μm, while average macular thickness value was 279.6+/−12.5 μm, and mean macular volume was 10.1+/−0.5 mm (Table 2).
The average RNFL thickness value provided by the software was used for further analyses.
The superior and inferior average is the average of thickness values in the superior or inferior 120° of the calculation circle; the temporal average is the RNFL thickness in the temporal 50°, and the nasal average is that of the nasal 70° peripapillary area.
Previously reported trends in annular flow average film thickness values for normal gravity are observed in microgravity and hypergravity conditions.
A validation was performed by using experimental data of average film thickness values of several representative food-grade fluids with coating capacity (emulsions and suspensions) obtained from the literature.
No significant differences were found between average GCIPL thickness values between preoperative and postoperative analysis.
In contrast, no differences were found in the average MCV and MCAT at 1 month after surgery (P = 0.186 and P = 0.318, resp .. Preoperative and postoperative average GCIPL thickness values obtained by automated segmentation were 60.72 ± 18.20 μm and 61.52 ± 17.37 μm, respectively, with no statistically significant differences between the two groups (Table 2).
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