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The average selection coefficient for the 1,000 best simulations was 1.2% with a 95% percentile between 0.8% and 1.8%.
The authors are mostly interested in determining the average selection coefficient at these sites.
The signed average selection coefficient excluding beneficial mutations, s d ¯, was used to quantify robustness.
In contrast, the estimated average selection coefficient for advantageous (S+) and disadvantageous (S-) mutations (Table 4) for each of these UCP loci are greater than three times the average selection coefficient for other genes [ 32].
We note that the average selection coefficient also increases although to a smaller extent in the absence of growth.
Genetic robustness thus can be measured as the signed average selection coefficient, excluding any possible beneficial mutations, s d ¯.
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The average selection coefficients vary only slightly with μ, with σ p taking about twice the value of σ q.
The average selection coefficients of the five most common isolates ranged from 0.03 to 0.83 across cultivars (Table 6).
The diversity reduction under the hitchhiking model employed [ 13] depends on the rate at which beneficial mutations occur, and their average selection coefficients (s).
The fraction of deleterious and beneficial mutations and the corresponding average selection coefficients are calculated while keeping a fixed value of the genomic mutation rate μ.
Field studies collated by Endler (1986) reported average selection coefficients of 0.33 for undisturbed environments and 0.30 for situations involving recent anthropogenic disturbance.
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