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Exact(14)
This is despite the fact that the average repeat length is shorter in subjects with 3 CAA interruptions.
This is despite the fact that ALS patients with 3CAA interruptions have a shorter average repeat length (27.5) versus patients with fewer interruptions (30.8).
In particular, the stated average repeat length of approximately 1 second reported in Ikegaya et al. (2004) should not be considered the true average length of repeats found intracellularly, but rather, an artifice resulting from the repeat detector program itself.
Despite their presence at all known MDS junctions, pointer repeats are short (average repeat length 4 bp between non-scrambled segments, 9 bp between scrambled segments [24]; current data still agree with these estimates) sometimes with mismatches, implying that pointer recognition alone is insufficient to direct accurate splicing.
Normally, for polyQ repeat expansion diseases, the relationship between repeat length and disease onset is such that longer repeats are associated with an earlier age of disease onset [13], [37]; thus, this trend for an earlier age of disease onset does not correlate with average repeat length.
The average repeat length was 82 bp; the longest IR found was 1,067 bp.
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We used average repeat lengths as placeholders for genotypes.
Average repeat lengths were also the same for cases and controls (cases 28.2, controls 28.2).
These average repeat lengths for our sample are higher than the mean for each motif type in our genome survey (Table 3).
However, based on the fact that mutability increases with microsatellite length [ 11] we suggest that the significant differences in average repeat lengths among cnidarian species might indicate differing mutation rates among species.
The average repeat lengths were different among various motifs ranging from 11.02 for (A/T) n to 58.84 for (AGT/ACT) n. > -wrap-foot> A total of 2034 SSR markers have been recently developed and reported on MaizeGDB website (www.maizegdb.org).
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