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Second, as a general limitation in bulk tissue analysis, studies of large brain regions can only report the average profile of all cells in the population.
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The first two columns give the cluster ID and number of transcripts present in the cluster and the following column provides a description of the average expression profile of all transcripts within the cluster.
These analyses will allow us to take into account each individual infant's own characteristics rather than relying on summary measures of the average risk profile of all patients in an individual trial.
The high resolution of our nucleosome maps, together with the independent analysis of early and late origins clusters were critical to disclose these different nucleosomal architectures, emphasizing the notion that the average nucleosome profile of all replication origins hides important variations in origin structure.
Only PHO86 was missed when MODEM was run on the averaged expression profile of all arrays.
For example, using Lapointe et al.'s dataset, the M-Normal statistical complexity quantifier first requires the computation of the probability distribution function of the average gene expression profile of all normal prostate samples.
We evaluated the average histone modification profile of all genes that change expression more than 2-fold in 2i versus serum.
The average expression profiles of all heat response genes are shown at additional file 2. The regulation relationships among modules are shown in the lower part of Figure 3.
For a TF, TIP builds a characteristic, averaged profile of binding around the TSS of all genes and then uses this profile to weight the sites associated with a given gene, providing a continuous-valued score of this TF for each gene.
For all marks, the distribution of SNEPs relative to gene position was consistent with the average profiles of the marks shown in Fig. 2 (Additional file 24).
The average profiles of most replicate pairs are highly consistent.
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