Exact(2)
BioCyc is a collection of metabolic pathways of 570 organisms and on average pathways in BioCyc are 4.2 times shorter than KEGG pathways.
The PANTHER classification system identified Wnt signaling (involving 5.5% of the total genes on average) and Gonadotropin-releasing hormone receptor (GnRHR) (involving 5% of the total genes on average) pathways with the highest gene associations.
Similar(58)
Branch lengths were calculated using the average pathway method [77].
Similar to the toy-network the average pathway lengths increases while r increases (Fig. 6 b).
Subsequently, it is not surprising that SuperPaths outperform their average pathway constituent's enrichment analysis scores.
For reference, in the average pathway, 10.7 cases (15.3%) and 8.4 controls (14.0%) were outliers.
For example, a cancer such as glioblastoma will have its pathway built as an average pathway for that cancer.
Either the average pathway deregulation score or the number of conserved high impact mutations can better predict patient outcomes.
For each pathway, we fitted a linear model controlled by the tissue source, where the average pathway expression was considered as the predictor of drug sensitivity.
The mutation probabilities were calculated as follows: an average pathway for carbon source utilization contains from 1 to 10 pathway specific genes (10 to 10 bp).
Here, we measure the average pathway length by the average shortest path (ASP), which is the average of the shortest routes from an input metabolites to each of the biomass metabolites.
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