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Salivary cortisol levels averaged 4.08 (S.D. 2.3) nmol/l at pretask baseline, and declined on average over the session to 3.45 (1.9) nmol/l immediately after the tasks and 2.87 (1.6) nmol/l 10 min later.
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To analyse these data we calculated mean tissue O2 levels during each of the four states and expressed these as difference scores from the mean O2 signal recorded (and averaged) over the whole session.
All participants performed the evaluation twice, with the SRTs averaged over the two sessions.
The average number of left/right forehand steps was averaged over the 6 sessions for each time-point.
Repeated measures ANOVA confirmed that, averaged over the two sessions, the number of rearings and leanings was different between strains (General Mean: F3,28 = 14.72, p < 0.001).
Repeated measures ANOVA revealed that, averaged over the two sessions, the percent time spent in open arms did not differ (General Mean: F3,28 = 1.63, NS).
Repeated measures ANOVA revealed that the percent open arm entries, averaged over the two sessions, did not differ (General Mean: F3,28 = 0.18, NS).
In all other analyses reported below, results for a particular contrast were averaged over the two sessions in which it was replicated.
Further pooling the trials together and computing an average over each session, normalized by the number of incorrect trials, we find no effect of session on report accuracy (one-way ANOVA F 9,40) = 0.77, p = 0.65).
The average over all sessions is shown in black.
The 30 mg/kg amitifadine dose, but not the lower doses caused a significant reduction in locomotor activity averaged over the one-hour session and reduced food motivated responding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com