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Concretely, we approximate this area using the average of true positive rate and false positive rate values by means of the following equation: (2) AUC = 1 + TP rate − FP rate 2, where TPrate = TP/ TP + FN) corresponds to the percentage of positive instances correctly classified and FPrate = FP/ FP + TN) corresponds to the percentage of negative instances misclassified.
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Therefore, our reconstructions present somewhat weighted averages of "true" values of optical parameters corresponding to excitation and fluorescent wavelengths.
Within each replicate, the average frequency of the favourable major QTL allele and the average level of true breeding values (DR, PT and TMI) were calculated, and subsequently averaged over all 50 replicates.
where represents the average number of true edges in M j.
For the 102 targets, the average properties of true actives and decoys were compared (Fig. 6).
The right-hand figures show the average number of true and false positives for different thresholds.t = 35 returned usert = 35 error eventt = 70 returned usert = 70 error event.
We used our mathematical analysis to calculate the average yield of true target genes discovered among the top-scoring hits at a specified false discovery rate (FDR).
As figure 5A shows, although reducing the mutagenesis density does not directly affect the cost of the sequencing experiment, it does increase the average yield of true targets discovered.
This score is then compared to: the expected random success rate, which is the average frequency of "true" causal genes in the N cases: <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0013920.e001.PNG" class= inline-graphic"/> ; the success rate Sclosest obtained by selecting the closest gene to the low-resolution (BXD) marker.
The average rates of true and false positives characterizing our weighted consensus network building method are illustrated.
For 200 repeated simulations, we calculated the average number of true and false positives for this method.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com