The phrase "average methylation of" is correct and usable in written English.
It can be used in scientific or research contexts, particularly in discussions related to genetics, epigenetics, or molecular biology.
Example: "The study focused on the average methylation of DNA across different tissue types to understand gene expression patterns."
Alternatives: "mean methylation of" or "typical methylation of".
While each particular cytosine may be either methylated or unmethylated, the RRBS technique measures the average methylation of a particular cytosine in the cell population, which results in a 0 to 100% range of values.
High grade cases F and I had an average methylation of 72% and 43% respectively, across all 27 CpG dinucleotides analyzed, while low grade samples 4 and 8 respectively had an average methylation of 19% and 35%.
The methylation status of each region was determined based on the average methylation of CpG sites in each region with a cutoff value of 0.1.
The results with 11 liver-derived clones showed an average methylation in the ALF promoter region of 55%, whereas oocyte-derived clones showed an average methylation of 8% (Figure 1E).
These samples had an average methylation of 43% and 52% (methylated/unmethylated ratio, given as percent), respectively, across all 35 CpGs analyzed, while samples I and 4 showed an average CpG methylation of 14% and 17%, respectively.
For assessing the pairwise standard deviations of neighboring CpGs in the Lsh KD and controls, first the average methylation of each CpG was calculated from all clones and then the standard deviations were determined.
Fractional methylation of a promoter region was calculated by averaging methylation of all CpG sites in that region.
The methylation level of nonsequenced residues was calculated by extrapolation of the average methylation levels of sequenced CpGs of the same promoter.
Analyses of average methylation levels of several CpG sites in the LINE-1 repetitive sequences usually show a high peaked distribution which obscures underlying modes due to differential methylation between CpG sites.
The average methylation status of the subtelomeric regions of all of the chromosomes of the MA pigs was significantly lower than that of the young pigs.
We also required that the absolute difference of the average methylation levels of a DM locus between two groups was >0.03 (Wang et al, 2010).
