Sentence examples for average methylation difference from inspiring English sources

Among six probes (999, 776, 80, and 77 bps downstream, and 308 and 170 bps upstream of TSS) targeting the promoter of NDN, one CpG site (308 bp upstream from TSS) was significantly less methylated in BPA-high samples (p-value < 0.02) with average methylation difference greater than 5% (Additional file 2: Figure S3B).

The difference in DNA methylation, according to methylation status (hyper- or hypo-) and the average methylation difference between MS and controls, was validated by an independent sample.

We identified 339 loci with an average methylation difference > 0.125 between any two toenail Hg tertiles.

However, it was excluded because its absolute average methylation difference between diandries and digynies was only 14%.

The average methylation difference between duplicate measurements was 0.6% for ATM, 1.1% for BRCA1, 1.0% for BRCA2, 1.3% for PTEN, 1.2% for RAD51C and 1.6% for TP53.

However, the stringent selection criteria (<0.1% FDR and absolute average methylation difference >15%) that we used to pick the top candidate sites caused an underestimation of the number of imprinted loci.

Data were processed through quality and dispersion filtering and with differential methylation analysis based on a combination of average methylation differences and non-parametric statistical tests.

Thus, the effect of the presence of inactivated X on the entropy was even more pronounced than what is seen with the average methylation differences.

MeDIP-on-Chip data were merged with gene expression microarray data by calculating the average methylation differences within 2 kb windows centered on TSSs of genes that had 5 or more MeDIP-on-Chip probes within the 2 kb window.

In total, 122 probes were identified with <0.1% FDR and average absolute methylation difference >15% (average absolute Δ β >0.15 from the Illumina array).

Basically, we derived the equations of DNA methylation mutation parameter θ m estimated by the average methylation state difference per site (π m ) and by proportion of methylation segregation sites (s m ).