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Discover LudwigThe phrase "average gene expression are" is not correct in written English.
It should be "average gene expression is" because "expression" is a singular noun.
Example: "The average gene expression is significantly higher in the treated samples compared to the control."
Alternatives: "mean gene expression is" or "typical gene expression is".
Exact(1)
Therefore, for many transcripts, the late up or down-regulations seem to be distinct from the early response – The early events seem to stabilize for most transcripts by 1 week post-injury, i.e. no more dramatic global changes in the average gene expression are observed and the level of expressions remains relatively constant.
Similar(59)
Differences in distributions of differentially expressed genes among ranges of average gene expression were tested using the Wilcoxon rank sum with Bonferroni post-hoc test in R.3.0.2 [ 63].
We have performed similar ANOVA for the SMG data set and found the same result, i.e., genes with GGN codons at their penultimate sites have higher expression value than the other four groups, with the average gene expression being 178.51 for GCN genes, 263.21 for GGN genes, 163.79 for GAN genes, 175.52 for GUN genes and 145.14 for NonG genes.
Gene expression differs significantly among the five groups (F = 3.07, DF1 = 4, DF2 = 163, p = 0.0180), with the average gene expression being 92.5 for GCN genes, 554.89 for GGN genes, 116.74 for GAN genes, 89.40 for GUN genes and 123.91 for NonG genes.
Gene silencing was not a main determinant of this loss of regulatory activity, since the average gene expression was essentially conserved.
A slightly higher induction of average gene expression was observed at the G2-M checkpoint in Xpc-/ mice, but this did not reach statistical significance (P = 0.086).
Proliferation/differentiation genes were computed by the simple criteria that their average gene expression was either RIα > Control > RIIβ (proliferation) or RIα < Control < RIIβ (differentiation) [see Additional File 3].
The relationship between GC3 and average gene expression is nonlinear and saddle-like for all four organisms (fig. 2), but the strength of the dependencies varies from organism to organism.
Average gene expressions were then calculated for each gene by taking the median probe intensity for all probes intensities in the replicate experiments that corresponded to each gene.
Biological fluctuations in gene expression are averaged out because of the ensemble (many cell) nature of the measurement.
Normalisation of the average sample gene expression was performed with the average Ct value of 18S rRNA endogenous gene control for that sample.
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