These mRNA over-expressions were correlated with increased levels of protein as confirmed by western blot analysis on cellular extracts for CXCL12 (4.4 average fold increase; p≤0.05) (Figure 4) and by ELISA on the supernatant of dermal equivalents for FGF7 (1.7 fold increase) (Figure 2).
The average fold increase in colony forming efficiency was 1.6-fold.
We found that genes with 2 to 2.49 folds increase by SAGE had an average fold increase of 2.3 by microarray, and genes with 2.5 to 2.99 fold increase by SAGE had an average fold increase of 2.7 by microarray.
The average fold increase for the other factors was only 8.5 ± 4.5 (standard deviation; n = 6 factors).
Clustering of the CCP expression data by fold change shows that the genes are highly expressed in mature pollen, with an average fold increase of 2.8.
Thus, the average fold increase above the time-matched saline controls was 2.39 ± 0.23, 4.27 ± 0.33 and 2.37 ± 0.25 at 1 hr, 3 hrs and 6 hrs, respectively.
Specifically, the average fold changes of these 'lipid' genes were 21.6, 17.6, 8.8, and 3.6, respectively at 6, 12, 24, and 72 h, compared with 1.7, 1.4, 2.3, and 2.4 average fold increases in susceptible plants during the same period.
The NOD/ShiLtJ, BALBcBy/J, C57BL/6J, and BTBR T+ tf/J strains had relatively large average fold increases in serum IL-6 levels (>8), whereas the A/J, 129S1/SvImJ, AKR/J, and DBA/2J strains all had average fold changes that were <1.
There was a statistically significant increase in serum total HGF at all post-dose time points, starting on C1D2 (or C1D3-4 fourfour multiple myeloma patients), with average fold increases of 2.0, 5.5, 8.0, 6.2, 6.2 and 12.3 at C1D2, C1D8, C2D1PRE, C2D1HR2, C2D8 and C4D8-14, respectively.
This value, which represents an average fold-increase of the IC50 when two or more papers report on the same combination of mutations, is obtained from the associated database.
During starvation, the average fold change increase found for toxin-antitoxin modules was 1.53, with ten gene pairs >2-fold upregulated and one >2-fold downregulated (Table S5).
