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While we are not the first to suggest that hydrogen bonds on average do not generally contribute to ligand binding affinities, this additional evidence is nevertheless interesting.
He called one "information-arbitrage" efficiency, which is essentially the same as Fama's definition, i.e. investors on average do not outperform the market, and he believed that markets were efficient in this respect.
While his work generally shows that investors on average do not outperform the stock market, a rough estimate of his definition of an efficient market, it says little about whether stock prices reflect the inherent value, or "fair value," of a company.
This suggests that mutual funds on average do not do better than the market on a risk adjusted basis.
For each individual regression, the TSX60 average and Industry average do not include the dependent stock's liquidity measures.
This suggests that in Germany employees, on average, do not fully exploit their vacation entitlements (see also Saborowski 2005 and Schnitzlein 2012).
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So if your pancakes are coming out below average, don't be discouraged.
Even without considering social and environmental costs, large dams on average don't make economic sense.
Adoption fees, on average, don't come close to covering the dogs' care while being sheltered.
But the average did not budge in May.
Indeed, by definition an average does not represent extreme values that can be significantly different.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com