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Twenty-seven consecutive patients affected by symptomatic femoral condyle OCD (average defect size 3.4 ± 2.2 cm2) were treated and prospectively evaluated by subjective and objective IKDC and Tegner scores at 2 years' follow-up.
Regardless of the GU condition, the size of CMA detected anomalies ranged from 50 kilobases to 57.4 Mb with an average defect size of 5.5 Mb, which is at the limit of the resolution of routine karyotype (Tables 2 5).
The average defect size in the MegaOATS subgroup was 5.3 cm (range, 3.1 to 7.1 cm; SD, 1.4).
The average defect size on the immediate post-surgical study was 2.2 x 2.4mm (ellipsoid area of 4.6mm2).
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The average recoil energy of the primary knock-on atoms, the total concentration of the defects, average defect sizes, and the increase in shear stress after a certain irradiation time are calculated for each spectral shifter.
According to this standardized choice of treatment the average defect sizes were 3.4 ± 2.0 cm2 in case of microfracturing, and 6.1 ± 2.6 cm2 in case of ACI (p < 0.001).
BMP-7 expression did not correlate with cartilage defect size; average expression in both intervention groups did not statistically significant differ (0.01 ± 0.22 pg/ml vs. 8.56 ± 24.22 pg/ml, p = 0.44, power 57.94%).
BMP-2 expression did not correlate with cartilage defect size; average expression in both intervention groups (ACI and microfracturing) did not statistically significant differ (121.90 ± 83.44 pg/ml vs. 119.03 ± 34.30 pg/ml, p = 0.14).
Defect size was the average of two defect tip measurements, from the front and back faces of specimen.
After twenty-two months, patients with a defect size of less than 25% had an average Rowe score of 94 and a mean external rotation deficit of 6°, whereas patients with a defect size of 25% or more had an average Rowe score of 90 and a mean external rotation deficit of 12°.
In comparison to these studies which only included chronic cases, our three patients with a defect size involving 25% showed excellent outcomes with an average Rowe score of 95 and an external rotation deficit of 5°.
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