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On average, data points from both TBPH LOF strains, TBPH−/− and GMR>TBPH-RNAi flies, were above those from controls (Fig. 4E).
While detailed comparison was not possible because our sampling times were much shorter - we had only 1-2 hourly average data points from the network for comparison - we did see differences, and discussed the importance of PT&R to provide street-level data at the height people are exposed.
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Each "one-day average" data point represents the one-day average of the fitted source fluxes from a number (typically 5-10) of individual ASM dwells.
The TRs within each block were averaged, resulting in a single average data point value per block that was used as the input to pattern classification analysis.
Mean CI′s were calculated from at least three averaged data points on the curve.
The number of averaged data points and their variance are discarded (see Results and Discussion: "Limitations").
If the segment consisted of > 5 averaged data points (corresponding to a minimum size of approximately 16.8 kb), we retained RJaCGH CNV calls with a posterior probability ≥ 0.6.
For a given temporal scale τ, the corresponding time series is derived by averaging data points in nonoverlapping windows of length τ from the original time series (τ = 1 corresponds to the original time series) (Fig. 2 B).
For the statistical analysis of normalized peak EPCS and normalized paired pulse ratio (PPR), paired comparisons were performed between averaged data points corresponding to the initial (baseline) and final (DHK), 5 min for each experiment.
First, the algorithm progressively down-samples the EEG post-stimulus time series per trial and per condition (i.e., for timescale t, the coarse-grained time series is constructed by averaging data points within non-overlapping windows of length t).
Specifically, for segments consisting of three to five averaged data points (corresponding to approximately 8.4 - 14 kb), we required a posterior probability greater than 0.75 and a log2 value equal to the mean ± 0.5*standard deviation of all log2 values (note, plus for gains and minus for losses).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com