The phrase "average coverage and" is correct and usable in written English.
It can be used when discussing the extent or quality of coverage in various contexts, such as media, insurance, or data analysis.
Example: "The report indicated that the average coverage and accuracy of the data collected were satisfactory for the study."
Alternatives: "typical coverage and" or "mean coverage and".
The overall sequencing results exhibited 22.2× average coverage and 86.0% of CpGs covered ≥5× on average (Supplementary Table S2).
Then, the nucleotides were replaced on the detected variant position in the reference genome with the alternative nucleotides if the position (1) had coverage of least 20% of the average coverage by reads in each library, (2) covered by at most twice of the average coverage, and (3) had 30 or higher mutation detection quality (QUAL) reported by GATK.
In addition, a nonlinear regression coefficient was calculated by fitting average coverage and GC content over 100 bp windows to a Gausian model using MATLAB.
Overall this also improved the average coverage and depth of all four loci (Additional file 7).
Table 5 shows the average coverage, and rmsd as reported by the native rigid method and by FlexSnap.
The former mapping produced a 13-fold average coverage and left 519 gaps, the latter one resulted in a 636-fold average cover and left 446 gaps.
Thirdly, we found that the resulting average coverages and enrichment factors were reproducible within each pool (more details in the Additional file 1 and Additional file 2: Table S1).
Nearly one in every four cellphone subscribers in the United States is now signed up with Verizon, which has established itself as having better-than-average coverage and customer service, if also slightly higher prices.
RCs were further subdivided into highly and medium redundant (HR and MR, respectively) according to their average coverage (>1,620 and comprised between 16.2 and 1,620, respectively).
In total, 38 putative diallelic SNPs were detected with ≥3X coverage (average coverage 78X) and an overall average estimated MAF of 0.07 (Table S8).
We retained consensus sequences with average coverage >8× and length >250 bp.
