"I can see two avenues for progress," he says.
These reports indicate that miRNAs play important roles in CRC development and progression, providing new avenues for GC diagnostic and therapeutic application (Ma et al., 2012).
Longer timelines for progression?
Basic research advances include the demonstration of circuit dysfunction, connectivity [ 3], and models of spread of pathologically misfolded proteins (tau, Abeta42, and alpha-synuclein) [ 4- 7] in explaining progression of disease and perhaps offering new avenues for treatment.
The interactions between tumor cells and surrounding tissue represent a crucial area of study in the elucidation of mechanisms of cancer development, progression and metastasis, and in providing novel avenues for cancer detection and treatment.
Concurrent advances in genome-modulating technologies, like gene silencing and genome editing, are providing ability to understand in detail the process of cancer initiation, progression, and signaling as well as opening up avenues for therapeutic targeting.
This result also opens up potential avenues for therapeutic and even preventive interventions to block tumor initiation and/or progression.
This method will be helpful for the further understanding of the mechanisms of the development and progression in cancers and may help develop new avenues for the prioritization of cancer-related genes with aberrant methylation for diagnosis and therapeutics.
With advances in research unraveling several mechanistic pathways and markers involved in the progression of the disease, a number of new treatment avenues for MDS are now being explored.
