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Our work thereby opens a wide avenue for identifying novel targets to improve the existing treatment and/or to develop new treatments for obesity and/or appetite disorders.
Finally, Mendelian forms of clefting provide another important avenue for identifying genes that may underlie the more common and isolated forms of clefts, especially if these syndromic forms can occasionally manifest as phenocopies of isolated clefts (e.g. Van der Woude syndrome, VWS [MIM 119300]).
Preclinical studies in animal models have provided an avenue for identifying the potential molecular neuropathobiology of drug-induced neuroadaptations [ 15].
An especially compelling avenue for identifying affected pathways is the use of interactomes, which define the molecular interactions in a cell.
Retinal cells derived from iPSCs are sufficiently faithful representatives of their in vivo counterparts (53) that they also present an excellent avenue for identifying and evaluating pharmacological agents capable of mitigating degenerative retinal diseases.
Given the functional enrichment analyses of the bicluster gene classifiers showing strong biological significance in breast cancer, this suggests a potential avenue for identifying new mRNA-based profiles for predicting disease recurrence.
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This, in turn, will open up avenues for identifying high-risk individuals and designing novel therapeutic strategies based on precise targeting of these genes.
"The work opens up therapeutic avenues for a cure, using or stimulating this enzyme, and avenues for identifying individuals among newly infected patients who have a chance of a spontaneous cure," they wrote.
This study opens up avenues for identifying new DNA damaging compounds from deep-sea bacteria.
This breakthrough observation opened up new avenues for identifying genes based on their expression pattern.
While genetic effect sizes appear to be smaller than originally anticipated, analyses considering possible interactions between both genetic and environmental factors, as well as methods that attempt to address the symptomatic heterogeneity of depression, may point the way to fruitful new research avenues for identifying clinically valuable predictors of treatment response.
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CEO of Professional Science Editing for Scientists @ prosciediting.com