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If generic versions are available, the challenges are even greater, since payers can promote a "generic switch" even if branded drugs have a new indication.
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But once treatment was available, the challenge seemed to be elsewhere.
Considering the number of new travel gadgets available, the challenge for iGo will be keeping up.
"But now, because so much music is available, the challenge is surfacing relevant music to listeners".
And while an abundance of new design concepts and energy-efficient fittings are now available, the challenge for architects is often how to choose among all these options.
"We know that some of this demand can be avoided if alternative services are available – the challenge is to provide the right care in the right place at the right time, and to ensure hospitals are only used when necessary and appropriate.
With a wealth of data now available, the challenge is to understand the skill and limitations of the data so they can be used routinely to support monitoring applications and to better understand environmental change.
Even when available, the challenge remains as to how to compile and summarize the data and thus map the burden of reproductive ill-health.
With increasing amounts of quantitative data being available, the challenge arises how we can use our typically qualitative knowledge about biological systems to explain this data.
Although a variety of robust and now widely adopted sequence alignment tools are available, the challenge of variant calling from aligned data remains.
With the broad range of natural and synthetic materials available, the challenge for biotechnology companies wishing to develop technologies for routine 3D hepatocyte culture is therefore choosing the appropriate material, fabrication method and final format.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com