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Although ADA is widely available, specificity may also be also sub-optimal, as we and others have previously demonstrated.
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However, even when the highest evidence level is available, their specificity as a biomarker of oxidative stress could be questionable, as in the case of oxLDL.
Unfortunately, the number of available donor specificities is rather limited, and typically only allow the transfer of either a glucosyl or a galactosyl residue.
All models assumed that no prior information (noninformative priors) about the unknown parameters (ie, prevalence, sensitivities, and specificities) was available, except that the specificity of culture was fixed at 100%.
Surgical procedures are typically performed without any form of image guidance as the available technologies lack specificity needed to provide nerve-specific imaging [ 12].
Such data has never been available with such specificity and timeliness.
In this work we review the available data on specificity determinants of crystal (Cry) insecticidal proteins as the Bt toxins most well characterized and used in transgenic crops.
Currently available inhibitors lack specificity for metalloproteinase because of a common Zn binding site in MMPs; thus, there is a need to identify selective MMP-13 inhibitors for osteoarthritis therapy.
By first separating types into structural groups and functional groups and then gradually relaxing types in a group into ancestor types, the IST which maintains the most specificity available may be determined.
Several commercial antibodies are available although their specificity has not been fully determined.
Since no complete list of targets for any TF is available, sensitivity and specificity cannot be calculated for any of these methods.
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