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Along with the rapidly increasing amount of data available, some aspects of our approach can be augmented by incorporating data from other dimensions, e.g., copy number variations or epigenetics, which could potentially help reduce the false positive rate and identify more explicit pathways.
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Limited information was available for some aspects of pain education, such as the number of hours or credits dedicated to pain education, limiting the extent to which the data can be utilised.
Limited information was available for some aspects of pain education and it could be argued that curricula might not fully or accurately represent the actual teaching and learning around pain.
In addition, some commercial solutions are available that cover some aspects of visualization needs (e.g., Strand NGS [ 93], BioDT [ 78]).
The evidences till now available have clarified some aspects of the very complex problem of cell signal integration, differential activation of signaling modules and intracellular compartmentalization of active complex that constitutes the inner causes of cellular response to changes in extracellular environment.
All the devices available, however, mimic only some aspects of real microgravity.
The application of more refined molecular tools and detailed evolutionary analysis to the genetic data now available will contribute to elucidate some aspects of this complex epidemiological situation.
Animal models of migraine are available, but they usually reflect only some aspects of the human condition and additional models are hence useful.
Among the concepts for which patient self-report could be valuable, and for which measurement appears feasible based on available psychometric data, are aspects of everyday functioning and complex activities of daily living and some aspects of executive functioning.
Names corresponding to mutant phenotype should be used when a mutant is available with the name describing some aspect of the corresponding phenotype.
In sum, each of these three hypotheses explains some aspect of the available data, but this data is currently not sufficient to decide equivocally for or against one of them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com