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Another available hypothesis is that the optimal mesenchymal state may be more suitable for the cell fate conversions, which is partially supported by the connection between EMT and stem cell characteristics (Hayashida et al., 2011; Mani et al., 2008).
However, in Mytiloida mitogenomes (Figure 1), the anticodon of tRNASer becomes GCU which does not support any available hypothesis.
However, the available hypothesis tests do not consider the interactions among genes in the gene network.
Existing plane hypotheses compete with newly created hypotheses to ensure that interest points are assigned to the best currently available hypothesis.
The aim of MSA is to arrange sequence regions relative to each other in a way that presents (to the tree-inference software) the best available hypothesis of homology at each and every position.
Given the uncertainty in the identity of pterioidean sister group, it is instructive to explore the effect of alternative combinations of outgroup taxa on the distribution of diagnostic morphological characters using the best available hypothesis of the ingroup relationships.
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Three main available hypotheses of hydrogen embrittlement are analysed in relation to austenitic steels based on the studies of the hydrogen effect on the interatomic bonds, phase transformations and microplastic behaviour.
Moreover, available hypotheses did not consider meiofauna diversity, which is characterized by direct development [188] but also by a small size, which allows organisms' resuspension and drifting over wide regions.
Based on this difference, a test could be developed to distinguish between these two currently available hypotheses about the mechanism of gene-specific selective sweeps in prokaryotes.
Phylogenetic relationships between gymnosperm families remain questionable (see Supplementary Figure S1 for a summary on available hypotheses on gymnosperm phylogeny), to the extent that even its monophyly and if a common ancestor is shared with flowering plants is still debated.
Although our results agree with most of the available hypotheses on the evolutionary loss of dlx genes in specific teleost lineages (i.e., dlx3a in zebrafish and dlx4a in medaka), we did detect dlx3a in cichlids and thus refute the cichlid-specific gene loss hypothesis of dlx3a put forward by Renz et al.[ 35].
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