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The available data identify NF-κB as an important effector of "programmed cell life" a set of evolutionarily conserved biochemical and molecular cascades designed to prevent cell death in a variety of physiological and pathological settings.
These tools efficiently use available data, identify critical data gaps for combined assessments, and prioritize which chemicals require detailed toxicity information.
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As Neuroskeptic has pointed out, this study is the culmination of work that has been going on for a number of years, with the novel contribution here being that Eklund's team illustrated the problem empirically, based on openly available data, identified the origin of the problems, and provided an alternative solution to standard methods.
These FDA warning letters are the only publicly available data identifying clinics/physicians who purchased and/or administered counterfeit Avastin, and the patient populations potentially impacted.
The available data identified regarding instrument characteristics, development, validation, responsiveness, and interpretation for each relevant PRO measure were reviewed against FDA PRO guidance criteria, the highest level of evidence currently required by a regulatory agency to support medical product labeling claims [[ 10]].
Available performance data identify considerable gaps in clinical care of diabetes across countries.
Detailed analysis of available sequence data identified transcripts of the new isoform in pig, cow, chicken and several fish (Table S1).
Over 46 differentially expressed genes were identified from a large list of potential targets by a) mining publicly available expression data (identifying 134 genes for quantitative PCR) and b) utilizing a commercial PCR array.
No routine available population data identifies the contribution of medical indication to preterm births in Brazil.
To this end we used publicly available data to identify 'estrogen independent' genes in ER + breast tumors and subsequently identified subgroups of ER + tumors based on molecular differences between tumors identified by these genes.
In k-anonymization, if the quasi-identifiers containing data are used to link with other publicly available data to identify individuals, then the sensitive attribute (like disease) as one of the identifier will be revealed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com