There are a number of algorithms available based on known experience of what kinds of sequences are most likely to give an immune response, e.g., Expasy (http://www.expasy.org/tools/) IEDB website (http://tools.immuneepitope.org/tools/bcell/iedb_input), or Antigen Profiler (http://www.pierce-antibodies.com/custom-antibodies/peptide-design-antigen-profiler.cfm).
Although no clear criteria for the acceptable degree of inter-observer agreement are available, based on our clinical experience, we decided prior to the study that differences exceeding 10° were determined as being unacceptable because they are likely to affect decisions on patient management.
The DQTC (now known as the Committee to Evaluate Drugs) monitors and evaluates the list of drugs available based on drug use patterns, experience, and current scientific knowledge monthly.
To this aim, the specific target is set to design and develop an analytical approach, which helps policy makers and relevant stakeholders to determine opportunities for LEDS and addressing the main relevant policy instruments available, based on the analysis of the practical experience with LEDS and related processes to date in their respective cities.
Finally, we had chosen to focus on analysis of data from HISWG and of data that are available based on the EHOs' and CBHOs' knowledge and experience of deploying health workers and providing services in conflict and postconflict periods.
Having developed this checklist based on experience and currently available literature, our future aim is to validate it.
Reaction parameters were estimated on the basis of publicly available literature data and some default assumptions based on experience with Biochemical Systems Theory [ 28], whereas the initial concentrations of particular sphingolipd species in each organelle were obtained from the LIPID MAPS database [ 29].
However, not all departments have such plans prepared and available, and some organizations have developed their own, often unformulated, procedures based on experience.
Was it based on experience?
