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mTOR positively regulates translation and ribosome biogenesis while negatively controlling autophagy, and is believed to set protein synthetic rates as a function of the availability of translational precursors [44].
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Automating the abstraction process and representing structured textual data as discrete, atomically coded values streamlines the availability of these data for translational research and outcomes analysis.
A previous study estimated that approximately 30% of the 4EBP1 expressed in cells is located in the nucleus, where it has a role in regulating the availability of EIF4E for the cytoplasmic translational machinery, by retaining EIF4E in the nucleus [ 16].
In addition, the availability of an increasing number of crystal structures of translational GTPases such as EF-Tu and EF-G have made it possible to probe the molecular details of GTP hydrolysis on the ribosome.
The evolving research landscape, with the emergence of the -omics field and the availability of large patient cohorts are creating a unique opportunity of translational epidemiology.
TAA is the preferred stop codon in prokaryotes because of the greater availability of TAA-cognate release factor(s) or lower levels of translational readthrough [ 31].
It is important to remark that the eye has been at the forefront of translational gene therapy largely because of the availability of appropriate disease targets and its suitable anatomic features.
To advance the science and clinical application of stem cell therapy, the availability of a highly sensitive, quantitative and translational method for tracking stem cells would be invaluable.
INTRODUCTION: To advance the science and clinical application of stem cell therapy, the availability of a highly sensitive, quantitative and translational method for tracking stem cells would be invaluable.
Moreover, it is known that regulation of r-protein genes is dependent on the availability of free ribosomal RNA by a translational feedback mechanism [ 24, 25].
This inverse relationship between co- and post-translational N-glycosylation likely arises from the availability of a larger pool of unglycosylated substrates available for post-translational N-glycosylation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com