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Another observation often made is that these markets have little to do with the underlying asset as the derivatives markets in these assets constitute many, many fold the availability of the "underlying" asset.
Note that while some may advocate also for Open Access to publications, the Blue Obelisk goals (ODOSOS) focus more on the availability of the underlying scientific data, standards (to exchange data), and code (to reproduce results).
This is due to the application-resource dependency and changing the availability of the underlying resources.
Solving this formulation provides an optimal abstracted topology to the CSP in terms of availability of the underlying resources.
Nowadays, a large number of important services – for instance e-commerce, healthcare and many others – depend on the availability of the underlying network.
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Elsewhere, there is concern about the threat to peer review posed by the selective publication of results or by outright fraud, and about the availability of the data underlying published conclusions.
Such films provide a vital reminder of what's at stake in the issue of availability and in the underlying question posed by Seitz and Ehrlich regarding the recognition of classics: classics are movies that expand the possibilities of the art, that offer templates not of imitation but of inspiration, that liberate other filmmakers and potential filmmakers.
Given the known tie between food availability and activity, especially in animals, it is possible that food availability was the underlying selection pressure for the evolution of activity-regulating mechanisms.
If required and assuming the availability of adequate data, revised estimates of the underlying epidemiology of a disease or risk factor would necessitate some re-estimation by national-level analysts (either via regression-based prediction or by performing additional runs of the population model itself).
This drives the determination of the operational service level requirements for data availability and synchronization that dictates the specifics of the underlying architecture.
Regardless of the underlying mechanism, the availability of an effective therapy for such patients would be particularly beneficial since there are few effective alternative therapies for them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com