The availability of this novel model will enable understanding of the pathogenesis of leptospirosis, as well as to study cutaneous barriers and epidermal interactions with this organism.
This is not only due to the availability of these novel datasets but also due to an increased interest into population structure as a potential confounding factor in the association studies.
The availability of the 2 novel DOBV strains as cell culture isolates enabled us to use them in chemiluminescence FRNT (c-FRNT) and characterize serum from selected patients also by neutralizing antibody titers.
Anti-MM treatment has advanced in the past decade with the availability of several novel agents that improve the survival rates of MM patients [ 1, 2].
The study utilizes the availability of two novel biocompatible PD solutions manufactured by the same company which differ selectively in the buffer employed, namely either pure lactate or pure bicarbonate.
Volatile anesthetics for sedation in the ICU are currently undergoing a revival, mainly due to the recent availability of a novel delivery system, the anesthetic conserving device (ACD).
The availability of some novel therapies elsewhere but not in Canada, can also suggest that Canada is lagging behind many countries in terms of 'state-of-the-art' practice.
The availability of our novel culture system offers a resource for pathological studies of neurodevelopmental diseases, furthermore, this hESC/hiPSC-derived organoid culture may also be used for various future biomedical applications, including cell therapies, drug discovery and toxicology studies.
In this study, we took advantage of a model of cardiac-specific overexpression of TRPC3 and the availability of a novel small molecule activator of TRPC3 channels.
The availability of several novel inhibitors of IGF-1R signalling (Ludwig et al, 2003; Garcia-Echeverria et al, 2003; Mitsiades et al, 2003) implies that clinical exploitation of any synergism between co-targeting of c-kit and IGF-1R will be practical.
