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A long-elusive protein that could have a serious impact in medicine has recently come to light because of the availability of the human genome sequence.
To the contrary, the availability of the human genome sequence has provided a breathtaking array of new information and has helped biomedical scientists develop treatment strategies for numerous previously intractable diseases by improving our ability to diagnose disease and to identify risk factors.
The recent public availability of the human metabolome and natural product datasets has revitalized "metabolite-likeness" and "natural product-likeness" as a drug design concept to design lead libraries targeting specific pathways.
With the availability of the human genome sequence, however, virologist Frederic Bushman at the Salk Institute in San Diego, California, decided to do a sweeping assessment of the chromosomal sites into which HIV integrates, hoping to pin down the virus's favorite places.
Due to the limited quantity and availability of the human material, amplifications were done on one sample but from two different tissues (testis and ovary).
Despite the availability of the human genome sequence, a respective full-ORF clone collection is far from being complete [ 20].
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The availability of the completed human genome sequence and reduced costs of sequencing have allowed large-scale screens to uncover genes that are somatically mutated in cancer.
Due to the limited availability of human serum, the concentration of human serum was kept at 10%.
Moreover, the paper also raises the critical issue of the availability of necessary human resources and technical capacity to execute detailed exposure assessments in resource-constrained settings.
The availability of the presently described human islet methylation profiling will allow future search and validation of surrogate tissues.
The major shortcoming is the lack of expertise in pharmacovigilance despite the availability of qualified human resource in the country.
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