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CT is the imaging modality of choice in radiotherapy treatment planning, due to the useful electron density information, availability of scanners and lack of spatial distortion.
The explosion of molecular imaging research over the last decade is partially, if not mostly, due to the increasingly wider availability of scanners dedicated to small animal studies.
Continued development and wider availability of scanners dedicated to small animal imaging studies, which can provide a similar in vivo imaging capability in mice, primates, and humans, can enable smooth transfer of knowledge and molecular measurements between species thereby facilitating clinical translation.
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Depending on experience with the technology and the availability of scanner time, MRI has become the first-line cross-sectional imaging technique for pulmonary disease in many departments [78].
The availability of EBCT scanners is modest, whereas the Multi Detector-Row CT (MDCT) scanners are more widely available and also allow for detection of coronary calcium.
The dotted arrow indicated the workflow for new tracers before the availability of preclinical scanners.
The availability of modern scanners with a high number of detector rows (16 or more) enables shortening acquisition times, therefore reducing the possibility of motion artefacts and increasing image quality.
Considering, the already strong diagnostic performance of PET/CT and MRI, high cost, and limited availability of PET/MRI scanners, integrated PET/MRI imaging might be reserved for selected cases of cardiac tumours were true benefit can be expected.
Moreover, given the increasing number of clinical MRI examinations and the widespread availability of MR scanners with high static magnetic fields (> 3 T), the consideration of possible risks and health effects associated with MRI procedures is gaining in importance and the term "dosimetry" has begun to be used also for non ionizing techniques as MRI.
18 Furthermore, the National Cancer Plan also aims to improve cancer diagnostics through increasing the availability of cancer scanners, for example.
With the increasing availability of CT scanners, there has been an explosion in the use of CT for various indications, 6 including pulmonary embolism.
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