The decisions as to whether to perform data reduction and which method to employ are influenced by several factors: (i) The availability of reference genomes: if sufficient reference genomes are available for a small number of dominant species then the sequences can be mapped to them and taxonomy and function inferred and the relative abundance of the transcripts calculated.
However, normalization of the data, availability of reference datasets, and scarcity of the data (specific measurements are not available for all patients) are non-trivial issues which are difficult to address.
The availability of reference samples in heritage studies is quite important.
In addition to labor and instrumentation, the difference in availability of reference substances makes this new method advantageous over chromatographic methods.
For meaningful real-time PCR results, availability of reference materials is critical in order to generate standard curves, which are not required for dPCR.
The Working Group considered variant allele frequencies in different populations and ethnicities, the availability of reference materials, and other technical considerations for PGx testing when developing these recommendations.
Scientists often employ multiple software tools to identify a spectrum depending on its chemical composition and the availability of reference spectra, and even the most experienced researchers can misinterpret results.
In this case, the availability of reference samples investigated and analyzed in the same conditions, allows us to extrapolate almost certain considerations on provenance of the obsidian artefacts found in the archaeological excavation.
In this way, the availability of reference obsidian samples from more areas as possible, is fundamental for both the reconstruction of the commercial trade and the knowledge of the artefact provenance.
Standardization of the experimental setup, including the cell source, cultivation conditions, and the use of media and solvents, would contribute greatly to the availability of reference-quality permeability data of chemicals, leading to more-general models and increased understanding of the structural dependence of the intestinal transport process.
The SAM spectral matching technique has been widely used in geological application (mineral mapping), however, the application of this kind of techniques is limited in water quality studies due to non-availability of reference spectral libraries.
