Therefore, in the current study we employed F-Aβ40 to take advantage of the current advances in optical microscopy and the availability of probes to track the protein accumulation in various cellular organelles.
We investigated either gene and/or protein expression, according to the availability of probes, as summarized in Table 1.
The latter approach depends on identification of targets that are upregulated at angiogenic blood vessels as compared to quiescent normal blood vessels and on the availability of probes that bind selectively and with high affinity to such targets.
On the other hand Whole Genome Sequencing protocols ensure the availability of probes mapping on the entire mitochondrial genome, therefore some missing variants derived from the exomes analyzed are linked to an incomplete covering of any mitochondrial genomes.
Increasing availability of streaming probe data allowing the observation of non-stationary traffic motivates the development of models capable of leveraging this information.
The availability of this probe will greatly facilitate molecular imaging studies on both the mode of action and the pharmacokinetics; and contribute toward the development of a new generation of polymyxin lipopeptides with superior activity against polymyxin-resistant Gram-negative 'superbugs'superbugs
The nuID and consequently the availability of the probe-sequence itself, enables one to explicitly model individual probe behaviors, which can be used in probe-selection [ 8], alternative-transcription modeling [ 9], background binding affinity modeling [ 10], or probe-affinity modeling [ 11].
However, the application of live cell imaging is limited by the availability of fluorescent probes compared with other techniques that utilize antibodies as probes.
The details of cardiac Ca2+ signaling within the dyadic junction remain unclear because of limitations in rapid spatial imaging techniques, and availability of Ca2+ probes localized to dyadic junctions.
However, the two datasets were not completely concordant and had several non-overlapping CNV loci, probably because the arrayCGH experiment has higher resolution due to the availability of more probes (400,000 vs. 54,000) but was performed in fewer breeds.
