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This occurs because of differences between the availability of RVs, different exposure pathways, and the availability of methodologies that support Tier 0 assessments.
The availability of methodologies that assist in this selection of relevant atomistic protein structural models from low-resolution X-ray data will lead to an enhanced understanding of biological structure and function.
As a food regulator, Health Canada's Food Directorate may be challenged about the availability of methodologies to support its proposed regulatory measures and standards associated with labeling of allergen and gluten sources.
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The rationale behind focusing on serum peptides is based on evidence that cancer formation and development involves change in proteins' and peptides' metabolism, and on the increased availability of methodology for screening the entire peptidome.
However, such studies will be critically dependent upon the availability of methodology that can accurately quantify 8-oxo-dGuo (24).
Despite the availability of proposed methodologies [ 12] there is considerable variance in the quality of the implementation.
The extent to which BRCA1/2 were screened reflects the availability of testing methodologies over the study period.
With the availability of improved methodologies, DNA sampling became almost exclusively based on saliva sampling (Oragene*DNA Self-Collection Kit; DNA Genotek Inc., Ottawa, Ontario, Canada).
The continuously increasing availability of analytical methodologies in combination with a constant decrease in detection limits has rendered biomonitoring both more accessible and more sensitive.
With the availability of this methodology, it will now be possible to investigate the approximate solution of other classes of IAEs systems.
In both these areas of investigation, additional work is needed to clarify these earlier findings because of either their small sample sizes or the current availability of improved methodology (e.g., biomonitoring) in exposure assessment.
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