The methods involved a pretest-posttest experimental design in which students were randomly assigned to either the experimental group, wherein they participated in the intervention, or the control group, wherein they attended classes without any auxiliary interactions.
Therefore an interaction with the CRD may be the main functional site for Groucho binding, but auxiliary interactions with the HMG DNA binding domain might further stabilize the complex.
In the remaining 20 articles, no further information was provided on whether the variables included in the imputation model were auxiliary variables or interaction terms.
In our review, approximately one-third of articles clearly specified the variables included in the imputation model, and only half of these commented on the inclusion of auxiliary variables or interaction terms.
This passive and open-loop stabilization works by consecutive and identical Hamiltonian interactions with auxiliary systems, here three-level atoms (the auxiliary ladder subsystem), followed by a partial trace over these auxiliary atoms.
Two models are described in this study: the main model of RNA-polymerase interaction, and the auxiliary model of mRNA-ribonuclease interaction in the polysome.
Additionally, differences in post-translational modifications of hERG1 channels and/or interactions with auxiliary proteins may play a role [18].
Although our results qualitatively show that differential expression of hERG1a and hERG1b may explain the observed variation in canine IKr, it remains to be shown to which extend post-translational modifications and/or interactions with auxiliary proteins influence the properties of native IKr.
In embryonic stem (ES) cells, targeting of de novo DNMT3A/3B enzymes to specific chromatin regions involves interactions with auxiliary factors in addition to their direct interactions with the nucleosomes [ 12, 13].
However, it can be a time-intensive process to impute multiple datasets, analyse the 'completed datasets' and combine the results; and the imputation model can be complex since it must contain the exposure and outcome variables included in the analysis model, auxiliary variables and any interactions that will be included in the final analysis model [ 22, 23].
However, electrophysiological assessment of K+ currents can often be inconclusive for the precise identification of contributing channels, due to the overlapping pharmacology (Johnston et al., 2010), modifications introduced by phosphorylation (Misonou et al., 2005) and interactions with auxiliary partners (Kerschensteiner and Stocker, 1999; Pongs and Schwarz, 2010; Vacher and Trimmer, 2011).
