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Assembly of individual product gene control modalities into synthetic networks has recently enabled construction of autonomously regulated time-delay or cell density-sensitive gene circuits, which trigger population-wide induction of product gene expression at a predefined time or culture density.
On the contrary, this paper focuses on summarization that is autonomously regulated by the user.
Thus, ERK5 differs from the other MAPKs in our models, in that it is autonomously regulated, through its unique phosphatase.
We propose that the targets preferentially rescued in CY262 animals represent age-1 targets that are autonomously regulated by intestinal age-1 activity.
Moreover, the nucleus also shows an autonomously regulated Ca2+ pool involved in certain signaling processes (14, 25).
López-Meyer and Nessler [ 18] isolated and characterised two autonomously regulated genes encoding TDC (Ca-TDC1 and Ca-TDC2) in C. acuminata.
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Thus, residents manually control the air conditioning in a passive service environment, whereas a location-based human-adaptive air conditioner autonomously regulates the temperature in a smart home according to residents' patterns of living or health status.
To further demonstrate whether the CRTC2/CREB complex autonomously regulates Insig2a, we used reporter assays in mouse primary hepatocytes.
Key Results and Conclusion In this interpretation, it is proposed that an individual leaf optimally and autonomously regulates stomatal opening on short-term (approx. 10-min time-scale) rather than on daily or longer time-scales.
To investigate possible effectors through which age-1 might non-cell autonomously regulate daf-16, we used transcriptional microarrays to identify age-1 target genes that could be non-autonomously regulated by age-1.
No change in the levels of lipogenic genes was observed in the cells (Figure 4F), suggesting that KRAP may not autonomously regulate lipogenic gene expression in the cells.
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