Of course, this system-autonomous explanation for LB pathology and its regional gradient does not exclude the possibility that transneuronal spreads of αS deposits and its uptake through neuronal soma are also taking part in human brain with PD.
Reasons provide an autonomous, non-causal form of explanation.
Idealizations can function in explanations that are autonomous in an important sense from lower level sciences.
It may also be difficult for the smaller firms to invest in technologies that support autonomous driving, should it prove popular.Another explanation for the small firms' endurance is the tacit support of Japan's government.
In philosophy of biology, reduction involves questions about how different biological disciplines and theories are related, and how biology itself is connected to physics and chemistry (e.g., is biology autonomous, possessing its own theoretical principles, explanations, and methods?).
Another possible explanation for the non-autonomous effects is that changes in cell shape and epithelial morphology in the furrow could affect the range or efficiency of intercellular signalling molecules, thereby affecting normal retinal development.
Such results find explanation in the semi-autonomous replicative mode of mitochondria, which would therefore continue to proliferate despite lack of cell division, in the senescent yet metabolically active G1-arrested cells.
We speculate that CBP may control higher order chromatin organization at all types of functional genomic sites, and that this could be part of the explanation for its cell-autonomous lethal phenotype.
An alternative explanation is that non-cell-autonomous mechanisms exert greater influence with age.
Since both cact and myd88 are thought to be canonical cell autonomous components of the Tl→NFκB signaling pathway a plausible explanation is that these genes are not haploinsufficient in the eye assay.
A plausible explanation comes from the finding that boundaries are not autonomous entities, but rather function in combination (likely pairwise) with other boundaries (Cai and Shen, 2001; Muravyova et al., 2001).
