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In the narrative that so many of us learned in school, the upheavals of the modernist epoch were, above all, formal developments, autonomous events within each discipline.
We speculate that the UPR may enhance neuronal plasticity events and functional recovery during the recovery phase after SCI related to neuronal functionality (cell autonomous events).
If cellular aging were due solely to progressive, irreversible cell autonomous events, then rejuvenation of a tissue or organ might be most successful through the introduction of new, young cells into that tissue or organ, as advocated by stem cell therapy.
This has led to the identification of known CRC genes as well as a collection of novel candidate CRC genes, demonstrating the potential of utilizing these isogenic HCEC lines to unravel the early cell autonomous events that contribute to CRC initiation and progression.
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An autonomous event comes into being, something comes to stand in its own right which "changes all that stand before it" (RB 25).
In order to utilize the proposed architecture, WSN developers have to design various types of autonomous event handlers for different subtasks of their specific WSN applications.
Apart from this, the proposed event-driven architecture is modular; therefore, a WSN application designer can take as many generic event dispatchers and autonomous event handlers as needed by a WSN application.
This customizable event-driven architecture is based on modular generic event dispatchers and autonomous event handlers, which will help WSN application developers to quickly develop their applications by adding the required number of event dispatchers and event handlers as per the need of a WSN application.
The evidence described strongly suggests that synaptic withdrawal from motor neurons following peripheral nerve injury is a neuron autonomous event and does not require active participation of the microglia.
The fact that initially, at least, only one cell of a pair (for the most part), lost a micronucleus, suggests that the nuclear loss is a cell autonomous event.
In disease models of chronic neurodegeneration, there is no evidence that microglia play an active role in either synaptic stripping or synapse degeneration, but the degeneration of the synapse and the envelopment of a degenerating terminal appears to be a neuron autonomous event.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com