The phrase "autonomous developmental" is correct and usable in written English.
It can be used in contexts discussing self-directed growth or progress, particularly in fields like education, psychology, or technology.
Example: "The autonomous developmental approach allows individuals to take charge of their learning process."
Alternatives: "self-directed development" or "independent growth".
In the absence of this triggering event, the pistil's autonomous developmental programme leads to organ senescence after a few days [ 1- 4].
This third source is comprised of non-linear epigenetic events that can cause variability at all phenotypic levels and that these epigenetic influences result from autonomous developmental processes with "emergent self-organizing properties".
These "inside-out" signals could be generated by growth factor signalling, or alternatively from intracellular pathways driven by autonomous developmental clocks [ 27], and would then effectively act as timers of myelination.
In order to ensure that the precise amount of myelin is formed at the right developmental stage and in the correct place, a key component of oligodendrocyte behaviour during myelin formation must be the integration of multiple extrinsic signals at the axon surface along with intrinsic programmes, such as autonomous developmental timers of differentiation.
Mutants lacking ForA, ForB or both showed no detectable phenotype, whereas disruption of the gene encoding ForC, which is expressed predominantly at late developmental stages, led to a cell autonomous developmental defect with the formation of aberrant fruiting bodies, suggesting this formin mediates actin remodeling during multicellular stages.
Loss of Adam17 results in a profound non-cell autonomous T cell developmental block in conventional knockout mice, and the underlying assumption from the previous literature was that absence of ADAM17 in thymic epithelial cells was the key cause of this block [25].
Without environmental signals, endogenous cues include the developmental or autonomous pathway that still can modulate flowering time [ 10].
In animals the somatic cell cycle is non-autonomous, subjugated to the developmental program encoded in the genome as a gene regulatory network (GRN) that both controls and is responsive to intercellular signaling (Davidson, 2006).
In other words, although their model is able to offer an explanation for cell differentiation in vulval development, it cannot capture the full non-autonomous nature of the developmental process, since it does not reproduce developmental trajectories, chreodes, in an accurate and fully time-dependent manner.
Expression of VAC14 in Vac14 −/− neurons reverses the synaptic phenotype, indicating a cell-autonomous and post-developmental role for VAC14 in regulating excitatory synaptic strength.
These results basically support the hypothesis that developmental and non-cell autonomous (glial) effects are shared in multiple neurodegenerative disorders.
