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A sub-group of 35 genomes was automatically annotated using the genome annotation system GenDB [ 42].
The differentially regulated gene probes were automatically annotated, using the corresponding IMGAG gene annotation (http://www.medicago.org/genome/IMGAG/) [97] when available, as well as the annotation of the best hit in TAIR [98] and Swissprot [99] databases.
The complete genome sequence of H. pylori was automatically annotated using the GenDB [ 60] genome annotation system.
For instance, for the Drug-Drug Interaction corpus, drugs were automatically annotated using the Metamap tool followed by the manual annotation of relationships by experts.
Draft and finished genomes were automatically annotated using an in-house version of the GenDB 2.2 genome annotation system.
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During the upload-process, every SNV is automatically functionally annotated using our in-house software tool snpActs (http://snpacts.ikmb.uni-kiel.de).de
The EST sequences were automatically trimmed, clustered and annotated using the EST2uni analysis pipeline [ 15].
Sequences obtained in this work can be found in GenBank [accession numbers AM713476 to AM743079] and MELOGEN [ 44]. EST sequences were automatically trimmed, clustered and annotated using the EST2uni analysis pipeline [ 43].
The B38 genome sequence was first automatically and then manually annotated using the MaGe system [ 28] http://www.genoscope.cns.fr/agc/mage and was then compared with the other sequenced H. pylori genomes.
The corpora from the CEMP task and BioSemantics group were annotated using two specific annotation guidelines, while the chapati curators considered all entities that could be automatically mapped to a CHEBI identifier.
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