Sentence examples for autoimmune cells from inspiring English sources

In most animal models of autoimmunity, including myocarditis, disease has been transferred to naïve animals with autoimmune cells (splenocytes or T cells), autoantibodies (7 ), or both, which provides compelling evidence that infections induce autoimmune diseases by immune-mediated mechanisms.

This necrosis factor in turn prompts the aberrant autoimmune cells to commit suicide through a carefully orchestrated program called apoptosis.

As Dr. Faustman describes, the mice that have been purged of autoimmune cells quickly regrow their islet cells, allowing the pancreas to reclaim its rightful role as insulin sweatshop.

It's unknown why some autoimmune cells would come to the rescue in emergencies, while others ravage vital tissue.

Yet autoimmune cells occasionally slip past this barrier, sometimes with devastating results: In multiple sclerosis (MS), for instance, these cells destroy the nerve fibers' protective sheath, crippling their victims.

This in turn impaired recruitment and reactivation of autoimmune cells in the CNS and ameliorated EAE.

However, the attenuated severity of EAE by BA was not a result of impaired autoimmune cell responses in the periphery.

Autoimmune T cells, such as CD8+CCR4+ T cells, may not be suppressed by Treg cells and thus may enter the circulation.

Psoriasis is a T-cell driven disease that causes epidermal hyperplasia, with an influx of autoimmune effector cells including monocytes, neutrophils, and dendritic cells [ 25].

Type 1 diabetes results from cell-mediated autoimmune β-cell dysfunction and destruction, whereas type 2 diabetes has been historically considered a metabolic disease (1).

We tested their effectiveness in autoimmune B cells and interferon-alpha-producing dendritic cells in vitro and in lupus-prone MRL-Fas lpr / lpr mice in vivo.