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In particular, the authors have suggested that, in the absence of full compliance with all nine criteria, the reliability and authenticity of results remain uncertain.
This molecular behavior is a well known phenomenon and has been described as an effective way to ensure the authenticity of results [ 10].
Reviewer #2: Weiß et al. develop a pipeline to assess the authenticity of results of analyses of ancient sedimentary DNA, and use this pipeline to test recently published results.
Although van Manen [ 39] and Benner [ 42] recommended carrying out a second interview in order to validate the researcher's interpretation and thus increase the authenticity of results, we conducted only one interview owing to the delicate and demanding nature of disclosure and to the difficulties encountered in setting up the first meeting.
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The authenticity of the results was supported by identical results from 2 independent genes of the BeV genome, sequence variations in the L and N genes from the positive samples, and negative results from all other mammals tested.
Using this approach, a simple and direct method is proposed to verify the authenticity of geomicrobiological results obtained from ice core materials.
"A scientist just needs to be aware that there's potential for people to question the authenticity of the results or the credibility of the science when it is associated with a particular policy decision," Benn says.
Further support to the authenticity of these results was provided by our unpublished observations that toxins incorporating 1b genotype derived HCV NS5A/B site (that is inefficiently cleaved by the 2a genotype encoded protease in HCV infected cells) resulted in a minor or undetectable enhancement in cytotoxicity upon treatment of infected cells.
The phylogenetic method can therefore signal caution in instances in which repeated direct sequence comparisons appear to have confirmed the authenticity of observed results; indeed, there is no guarantee that re-analysis should not suffer from the same systematic error or persistent contamination as in the initial analysis.
The authenticity of the results, including sequence analysis data, is extensively discussed.
The sample size and power influence the accuracy and authenticity of statistical results indeed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com