In this study we found that SAHA was significantly less effective at augmenting vaccinia virus spread in vitro than TSA.
The prime-boost strategy, which entails sequential administration of different types of vaccination (e.g., DNA electroporation followed by injection with a recombinant virus), augments immunogenicity of transgenes.
Peptide mimotopes provide a strategy to augment human immunodeficiency virus 1 (HIV-1) specific carbohydrate reactive immune responses.
No cell population was considerably augmented by the virus.
Thus, human liver-specific miR-122 has been shown to functionally augment hepatitis C virus (HCV) replication [ 25], while more than half a dozen human miRNAs, including miR-199a-3p miR-199a-3p miR-199a-3p5p, are found to repress hepatitis B virus (HBV) replication [ 26].
E1B-55 kD-deleted adenovirus has been shown to act as a helper virus and augment the expression of the accompanying cytokine genes delivered by replication-defective adenoviral vector (Motoi et al, 2000).
Recently, the fact that carrying at least any two viruses augmented the risk to be transferred to PICU has been reported [5].
Moreover, use of PCR has augmented detection of viruses that are difficult to identify with conventional methods, including human rhinovirus (HRV), human coronavirus (hCoV), human metapneumovirus (hMPV), and human bocavirus [ 7, 8].
Addition of rIDE at 2.5 hr after infection with VZV resulted in an increase in the size of plaques (P<0.0001 for both rIDE vs. BSA control and rIDE vs. Buffer, Fig. 4B), suggesting that rIDE not only augments infectivity of cell-free virus at entry but also promotes infectivity through enhanced cell-to-cell spread of virus.
In the current study we set out to examine the ability of a panel of HDIs to augment oncolytic activity of vaccinia virus.
