Sentence examples for augments the activity from inspiring English sources
However, in view of findings indicating that activated PARP-1 highly augments the activity of ERK in the nucleus even in the absence of DNA damage [ 3, 4], a different therapeutic potential of PARP inhibitors is examined in breast cancer cells lacking BRCA mutations.
This is the first description of a mitochondrial pool of STAT3 that augments the activity of the ETC.
Indeed, the increased expression of Nfkbia (i.e. IκBα), cyclinD1, and MMP-9, which are predominately regulated through classical NF-κB pathway [51] in our microarray and QRT-PCR assays (Figure 1) is suggestive of the fact that TWEAK also augments the activity of classical NF-κB signaling pathway in muscle cells.
S6K is also phosphorylated by TORC1, and in turn it phosphorylates and augments the activity of several translation factors (Ma and Blenis, 2009).
Furthermore, treating ER+ breast cancer cells with a combination of ACT1 and tamoxifen or HER2+ breast cancer cells with ACT1 and lapatinib augments the activity of these targeted inhibitors.
The addition of sulbactam to ceftriaxone treatment not only augments the activity of ceftriaxone against β-lactamase-producing bacteria but also maintains its cost-effectiveness (once or twice daily administration).
Since MsrA protects lens cells against oxidative stress, we hypothesized that any reducing system needed for MsrA activity might be activated by oxidative stress and thereby augment the activity of MsrA to defend lens cells under these conditions.
Given that several catalytic activities are required for plant polysaccharide degradation and dissolution, screening of carbohydrate active enzymes (CAZymes) by ToF-SIMS could be achieved by augmenting the activity of a known cellulase cocktail [ 1].
Second, to augment the activity of GCHI, the folE gene from E. coli was replaced by the mtrA gene from Bacillus subtilis.
This is expected to significantly increase the potential applications of these peptides as tools for augmenting the activity of lipid nanoparticles used in gene delivery.
