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This is because the traits (e.g. life-history bottlenecks) that act to align the fitness interests of particles (e.g. cells) in a collective can also act to diminish the extent to which those particles are bearers of heritable fitness variance, while augmenting the extent to which collectives of such particles (e.g. multicellular organisms) are bearers of heritable fitness variance.
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On the contrary, when cells were treated with a relatively high dose of adriamycin (0.4 μg/ml) cells became apoptotic, and the simultaneous presence of a c-ABL kinase inhibitor STI571 augmented the extent of apoptosis.
Interestingly, PMA treatment augmented the extent of polyploidy in CIB1oe cells compared to mock.
Increasing the concentration to supra-physiological levels such as 10 μM failed to augment the extent of inhibition afforded by Pred.
Moreover, the co-treatment of human glioma spheroids with DCA plus TMZ augmented the extent of cell death as compared with DCA alone.
However, a combination of MLN4924 and bendamustine significantly augmented the extent of double-stranded DNA damage and led to enhanced apoptosis.
Conventionally, mulches increase the yield and water use efficiency (WUE) to a great extent by augmenting the water status in the root zone profile.
Thus, these data suggest that breast cancer may enhance the extent of osteoclastogenesis by augmenting the pool of osteoclast progenitor cells.
This suggests that some breast cancers may increase the extent of osteoclastogenesis by augmenting the pool of osteoclast progenitor cells via tumor-derived IL-11.
The data obtained in the first stage was also augmented to the extent necessary for this purpose.
Using a co-solvent based method and 25 drug candidates, the data suggested, on the whole, that the surfactants and the selected cyclodextrin seemed to best augment the extent of supersaturation but had variable benefits as stabilizers, while the pharmaceutical polymers had useful effect on supersaturation stability but were less helpful in increasing the extent of supersaturation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com