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Given that several catalytic activities are required for plant polysaccharide degradation and dissolution, screening of carbohydrate active enzymes (CAZymes) by ToF-SIMS could be achieved by augmenting the activity of a known cellulase cocktail [ 1].
This is expected to significantly increase the potential applications of these peptides as tools for augmenting the activity of lipid nanoparticles used in gene delivery.
We have shown that the plant extracts Aegle marmelos and Syzygium cumini stimulate glucose uptake in skeletal muscle by augmenting the activity of the regulatory molecules; phosphatidyl inositol-3-kinase (PI3K), AMPK and GLUT-4 (Anandharajan et al. 2006).
Accordingly, we developed a strategy to overcome this rate-limiting step by augmenting the activity of cholesterol oxidases in M. neoaurum strains to enhance their transformation productivity of sterols to valuable steroids.
21, 22 Animal studies also implicate increased energy expenditure by augmenting the activity of the inhibitory neurotransmitter γ-aminobutyric acid.
A further mechanism that may be exploited to treat PH is to improve endogenous NO bioavailability by augmenting the activity of endothelial NO synthase (eNOS).
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However, in view of findings indicating that activated PARP-1 highly augments the activity of ERK in the nucleus even in the absence of DNA damage [ 3, 4], a different therapeutic potential of PARP inhibitors is examined in breast cancer cells lacking BRCA mutations.
Since MsrA protects lens cells against oxidative stress, we hypothesized that any reducing system needed for MsrA activity might be activated by oxidative stress and thereby augment the activity of MsrA to defend lens cells under these conditions.
Transcriptional control is exerted with the help of regulatory sequences that are found associated with a gene, such as the promoter sequence, a region near the start of the gene, and enhancer sequences, regions that lie elsewhere within the DNA that augment the activity of enzymes involved in the process of transcription.
Even though high DO concentrations are required to augment the activity of nitrifiers in the reactor, denitrification gets inhibited by excess oxygen.
Second, to augment the activity of GCHI, the folE gene from E. coli was replaced by the mtrA gene from Bacillus subtilis.
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