Sentence examples for augmenting subsequent from inspiring English sources

Notably, glucocorticoids may up-regulate TLRs on microglia, augmenting subsequent neuroinflammatory responses (Frank et al. 2010; Garate et al. 2013).

However, DA release induced by HPC stimulation has been shown to augment subsequent hippocampal-evoked neural activity of NAc neurons (Floresco, 2007; Floresco et al., 2001b).

IgG-inducing active receptor conformations dampened or augmented subsequent cAMP stimulation by isoproterenol, depending on whether receptor internalization was attenuated or not.

Pre-incubation with most cAMP-stimulatory autoantibodies also augmented subsequent isoproterenol stimulation of intracellular cAMP suggesting that they possibly promote the agonist-coupled high-affinity state of the receptor.

(3) Natural selection and genetic drift require genetic variation, which arises originally from mutation and can be augmented by subsequent gene flow.

Also, the mechanism(s) for how MHV-68 infection augmented the subsequent fibrotic response to bleomycin were not defined.

4. Cost-effectiveness analysis - The health system perspective will be used for the primary analysis, and will be augmented in subsequent analysis with direct non-medical costs.

Another limitation of the Ishak/Knodell fibrosis score is its nonlinearity as it includes scores 0, 1, 3, and 4. The Metavir scoring system was designed specifically for patients with hepatitis C using a sum of experience-based opinions of 10 pathologists augmented by subsequent stepwise discriminant analysis [ 27].

Of importance, inhibition or depletion of histone deacetylase 6 (HDAC6) promotes the hyperacetylation of Hsp90, thus augmenting the polyubiquitination and subsequent degradation of Hsp90 client proteins (17– 20).

This suggests the possibility of an amplification loop such that small changes in the level of pEphA2 S897) may be augmented by the subsequent loss of CLDN4 from the tight junction that results in further EphA2 phosphorylation.

It is possible that expression of mutant PC-2 can result in p57 downregulation by augmenting Id2 nuclear import and subsequent inhibition of p57 transcription [ 17].