Sentence examples for augmenting gene expression from inspiring English sources

By contrast, expression of TCF2 was not restored by the histone deacetylase inhibitor TSA, but when combined with a low dose of 5-aza-dC, TSA exerted a synergistic effect augmenting gene expression.

The expanded result for dynamic range of GFP expression in high antibody-producing clones with enhanced qAb via gene amplification system and/or cis-acting element for augmenting gene expression may be helpful to meet the industrial standard.

Proteins expressed across many cell types require augmented gene expression flexibility to adapt to local conditions.

Of the five hypersensitive sites that define the LCR, only 5'has has been shown to augment gene expression in vitro in both transient and stable assays, as well as in transgenic mice.

More recently, PPI network information has been used to augment gene expression measurements to identify condition-specific response complexes [32], [33].

This landscape suggests that miRNAs, being gene regulatory factors via translational repression, were down-regulated to yield augmented gene expression in response to H1N1 infection.

The 5′ flanking region of the AFP gene consists of several enhancer like sequences [ 24] where one of the core enhancer region can augment gene expression in an engineered construct [ 25].

One obvious possibility is that mhtt (with its abundant polyQ residues) is recruiting TG2 (an enzyme which crosslinks glutamines and lysines or polyaminates glutamine residues) to relevant promoters to silence (or augment) gene expression.

Transcriptional activation of IL-8 is controlled primarily by NFκB; however, other transcription factors such as activating protein-1 and CAAT/enhancer-binding proteins can also regulate IL-8 expression and act synergistically with NFκB to augment gene expression [ 90, 91].

TSPCs cultivated on electrospun nanofibers showed augmented tenogenic gene expression (Yin et al. 2010) and increased ECM production (Xu et al. 2014).

These results suggest that overexpression of TrpC3 strongly augments BNP gene expression, but that this effect depends upon co-stimulation with hypertrophic agonists such as PE.