Sentence examples for augmented the phosphorylation of from inspiring English sources

We observed that histamine augmented the phosphorylation of STAT1 through both H1 and H2 receptors.

Accordingly, curcumin augmented the phosphorylation of c-Jun and JunB, the downstream transcription factors of JNK and ERK, in THP-1 cells.

BSO augmented the phosphorylation of BIMEL and the expression of MCL1, but reduced the level of MCL1 that co-precipitated with BIMEL.

The addition of chemerin augmented the phosphorylation of p38MAPK at 5 to 15 minutes compared with unstimulated RA FLSs, but the level decreased at 30 minutes, whereas phosphorylation of JNK1/2 was not promoted by chemerin stimulation.

Also, studies on Nrf2−/−MEFs revealed enhanced IKKβ activity, augmenting the phosphorylation of IκBα and its subsequent degradation [ 25].

Notably, DNA-PK augments the phosphorylation of Chk2 by ATM, hence increased phosphorylation of Chk2 upon SMAR1 overexpression can be reasoned to enhanced recruitment of Ku70 to DSB sites, which results in the formation of holoenzyme DNA-PK.

The Western blot results revealed that ME not only augments the phosphorylation of ERK involved in the MAPK pathway though effects of ME on MAPK cascade should be further clarified in future studies, but also promotes GLUT4 translocation which is more relevant to the glucose lowering effects involved in the PI3K-AKT/PKB metabolic pathway.

Moreover, LiCl augmented the phosphyorylation of PKC δ, but not Akt phosphorylation (data not shown).

Treatment of cells with inhibitors (okadaic acid and calyculin A) of PP2A, a phosphatase that decreases ATM phosphorylation, augmented the IR-induced phosphorylation of ATM (Fig. 4B), indicating the involvement of PP2A in the regulation of ATM activity in response to DNA damage.

BSO addition augmented the expression and phosphorylation of MCL1 at Ser and/or Thr, whereas ATO alone did it only minimally.

In addition, polyADP-ribosylated PARP-1 highly augmented the activity of phosphorylated ERK, enhancing phosphorylation of ERK-targeted transcription factors, core histone acetylation, and the expression of ERK target genes, some of which are oncogenes [ 3- 6].