Sentence examples for augmented sensitivity to from inspiring English sources

Those stable transfected pool clones also did not show any augmented sensitivity to the TNF death signal.

Treatment of MCF-7 breast carcinoma cell line with antagomiR-451 via transfection and doxorubicin revealed an augmented sensitivity to the drug uptake [ 81].

Parg −/− ES cells generated by the disruption of exon 1 also show augmented sensitivity to γ-irradiation, alkylating agents, and cisplatin treatment.

In concordance with the augmented sensitivity to CDDP, the density of DNA adducts was higher in HUH6 cells compared with HepT1 cells and increased in both lines with exposure time and drug concentration.

The augmented sensitivity to TRAIL resulted from the redistribution of DR4 (but not DR5) and the various DISC components to lipid raft subdomains of the plasma membrane in cisplatin-resistant cells.

This alteration might be explained by the phosphorylation of the myosin light chain, rendering structural changes within the sarcomeres and augmented sensitivity to Ca2+, as reported by Szczesna et al. [ 14].

Reducing OA-augmented sensitivity to NGF has potential to improve OA pain while retaining the normal homeostatic actions of NGF.

This theory is also corroborated by the findings of augmented cough sensitivity to inhaled capsaicin (Johansson et al. 2002; Millqvist 2000; Millqvist et al. 1998, 2000; Ternesten-Hasseus et al. 2002b).

Indeed, the augmented coronary reactivity of the HF rats was due either to an augmented sensitivity of the SMCs to NO in the rats displaying body weight gain compared to the control ones or to an improved ECVA in the animals with no body weight gain.

However, in the context of decreased Purkinje IP3R abundance, augmented sensitivity (whether comparable to other cell types or greater) could potentially restore normal IP3 response if the IP3R1 is not lowered as drastically as the factor of 10 used in the Hernjak [ 35, 54] model.

The deficiency of vitamin E led to the retina degradation, the augmented lipofuscinogenesis in RPE, the decrease in the PUFA level in rod outer segments and RPE as well as the augmented sensitivity of the retina to photo-oxidative damage (Hayes 1978; Farnsworth et al. 1979; Beatty et al. 2000).