Sentence examples for augmented sensitivity of from inspiring English sources

That is, when AT2 receptors were exogenously activated or when the counterbalancing actions of AT1 receptors were blocked, an augmented sensitivity of the high-pressure baroreceptors became evident.

The augmented sensitivity of cisplatin-resistant cells to TRAIL (TNF-related apoptosis-inducing ligand) signaling results from the redistribution of the death receptor 4 (DR4) to lipid raft subdomains within the plasma membrane.

Indeed, the augmented coronary reactivity of the HF rats was due either to an augmented sensitivity of the SMCs to NO in the rats displaying body weight gain compared to the control ones or to an improved ECVA in the animals with no body weight gain.

The deficiency of vitamin E led to the retina degradation, the augmented lipofuscinogenesis in RPE, the decrease in the PUFA level in rod outer segments and RPE as well as the augmented sensitivity of the retina to photo-oxidative damage (Hayes 1978; Farnsworth et al. 1979; Beatty et al. 2000).

Furthermore, in agreement with previous data (Wang et al, 2003; Voboril et al, 2004), inhibition of NF- κB also augmented sensitivity of HT-29 tumour cells to 5-FU, the most common antimetabolite used for the treatment of CRC and other types of solid tumours.

In concordance with the augmented sensitivity to CDDP, the density of DNA adducts was higher in HUH6 cells compared with HepT1 cells and increased in both lines with exposure time and drug concentration.

The augmented sensitivity to TRAIL resulted from the redistribution of DR4 (but not DR5) and the various DISC components to lipid raft subdomains of the plasma membrane in cisplatin-resistant cells.

Overall, we observed three different phenotypes that were associated with the presence of p53: reduced, unchanged or augmented sensitivity for extrinsic cell death induction by TRAIL.

Parg −/− ES cells generated by the disruption of exon 1 also show augmented sensitivity to γ-irradiation, alkylating agents, and cisplatin treatment.

Treatment of MCF-7 breast carcinoma cell line with antagomiR-451 via transfection and doxorubicin revealed an augmented sensitivity to the drug uptake [ 81].

This alteration might be explained by the phosphorylation of the myosin light chain, rendering structural changes within the sarcomeres and augmented sensitivity to Ca2+, as reported by Szczesna et al. [ 14].