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These effects ultimately lead to an augmented sensitivity.
Those stable transfected pool clones also did not show any augmented sensitivity to the TNF death signal.
Treatment of MCF-7 breast carcinoma cell line with antagomiR-451 via transfection and doxorubicin revealed an augmented sensitivity to the drug uptake [ 81].
Overall, we observed three different phenotypes that were associated with the presence of p53: reduced, unchanged or augmented sensitivity for extrinsic cell death induction by TRAIL.
That is, when AT2 receptors were exogenously activated or when the counterbalancing actions of AT1 receptors were blocked, an augmented sensitivity of the high-pressure baroreceptors became evident.
Parg −/− ES cells generated by the disruption of exon 1 also show augmented sensitivity to γ-irradiation, alkylating agents, and cisplatin treatment.
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Reducing OA-augmented sensitivity to NGF has potential to improve OA pain while retaining the normal homeostatic actions of NGF.
Introduction of p-doping to the polymers results in augmented anion sensitivity, which is ascribed to the effect of synergy between low-level p-doping in a polythiophene polymer and hydrogen bonding.
Inhibition of PhoPQ signaling appears to contribute to most of the NO-mediated abrogation of the ATR in log phase bacteria, because the augmented acid sensitivity of phoQ-deficient Salmonella was not further enhanced after RNS treatment.
Chronic, severe stress and subsequent activation of the hypothalamic-pituitary-adrenal axis are associated with augmented pain sensitivity [ 24].
This theory is also corroborated by the findings of augmented cough sensitivity to inhaled capsaicin (Johansson et al. 2002; Millqvist 2000; Millqvist et al. 1998, 2000; Ternesten-Hasseus et al. 2002b).
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