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Open image in new window Fig. 13 Schematics of initial 16 sample points (red) selected by UD for a two-dimensional design problem and augmented sample point (green) for model validation.
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The researchers exposed the subjects to one of two house dust samples vacuumed samples containing 0.41 mg/g (DEHPlow) or augmented samples containing 2.09 mg/g (DEHPhigh)—for 3 hours.
To augment sample sizes, we repeated several crosses and extracted DNA from mature planulae.
To address this rejection problem, we propose the SampleSearch scheme that augments sampling with systematic constraint-based backtracking search.
A detailed description of all observed coding variants can be found in Table 2. To further validate the Belgian association results, we first augmented the sample size by genotyping additional unrelated Belgian cases and controls (239 CD, 96 UC and 107 shared controls), and combining them with the 440 CD and 137 UC trios previously genotyped.
Stage 1 selected for the HPV16 analysis, which required HPV16 DNA negativity at enrollment, and Stage 2 augmented the sample for the HPV18 analysis, which required HPV18 DNA negativity at enrollment.
Where enrolment was inadequate, snowball sampling was used to augment the sample size or to address deficiencies in the sample mix.
Should we have a suitable sample size of cytogenetically normal cases after this evaluation, possibly augmented by samples from the genetically related population in Antioquia, we intend to perform a genome-wide single nucleotide polymorphism (SNP) screen to identify autism susceptibility genes.
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